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Title: Platelet function in patients with polymorphisms of GP IIb/IIIa and cyclooxygenase
Author: McCaslin, James
ISNI:       0000 0001 3622 9884
Awarding Body: Newcastle-Upon-Tyne University
Current Institution: University of Newcastle upon Tyne
Date of Award: 2005
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Platelets contribute to the progression of atherosclerotic disease by adhering to the subendothelial matrix at sites of shear-induced mechanical injury to the vessel. The understanding that genetic factors play a role in the development of atheroma led to recent interest in polymorphisms of platelet receptors as a possible basis for this. Furthermore, there is a growing body of evidence to link these polymorphisms with resistance to antiplatelet agents, the implications of which are not yet fully appreciated.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available