Use this URL to cite or link to this record in EThOS:
Title: Hepatitis C: genetic and host factors associated with outcome following infection
Author: Price, David Ashley
ISNI:       0000 0001 3500 0703
Awarding Body: Newcastle-Upon-Tyne University
Current Institution: University of Newcastle upon Tyne
Date of Award: 2008
Availability of Full Text:
Access from EThOS:
Data on 1113 patients was collected and entered into a database. The North East cohort of patients infected with HCV were not different from other cohorts. Risks for progression of liver disease of heavy alcohol use, male sex and length of time of infection were similar to those reported in other national cohorts. A major effect of HCV on lipid homeostasis was seen in this cohort. The rate of steatosis amongst patients with chronic HCV infection was 50% similar to other studies and it would appear that a high BMl and viral genotype were the most important factors in the development of steatosis in this cohort. As in other studies hypolipidaemia was also seen in those with chronic HCV infection and this appeared to resolve with treatment.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available