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Title: Isolation and characterization of stem cell phenotype in benign prostatic hyperplasia and prostate cancer.
Author: Gilmore, Paul Edward
ISNI:       0000 0001 3500 2987
Awarding Body: University of Manchester
Current Institution: University of Manchester
Date of Award: 2008
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The prostate epithelial stem cell has been proposed as the primary origin of neoplastic change in prostate cancer. However, due to a lack of specific markers, such cells have been profoundly difficult to isolate. We propose that the Hoechst 33342 dye efflux assay 'Side Population' originally developed to isolate a stem cell enriched haemopoietic stem cell population from bone marrow provides a method for identifying the cancer stem cell origin in prostatic adenocarcinoma.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available