Vulval intraepithelial neoplasia is a pre-malignant skin condition which is characterised by distressing symptoms of pruritis and dyspareunia; H is increasingly ' common in younger women and is often resistant to treatment. Radical vulval surgery is inappropriate because of the low rate of progression to malignant it disease and conservative excisional treatment often fails. These studies are an attempt to develop an acceptable alternative treatment which gives good long term results and maintains the normal vulval architecture.