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Title: Structural studies on polyketide enzymes
Author: Dall'Aglio, Patrick
ISNI:       0000 0001 3402 5976
Awarding Body: University of Bristol
Current Institution: University of Bristol
Date of Award: 2008
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Polyketides are a class of secondary metabolites that includes compounds with antibiotic and anticancer properties. In type I polyketide synthesis, the individual activities are arranged into large | polyproteins, while in type II polyketide synthesis enzymes are encoded separately. Streptomyces coelicolor actinorhodin acyl carrier protein synthase (AcpS) IS a promiscuous enzyme involved in type II polyketide synthesis that catalyses the transfer of the phosphopantetheine chain from coenzyme A (CoA) to acyl carrier protein (ACP).
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available