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Title: Biochemical and cellular analysis of ADP-ribosylation factor like 8b (Arl8b)
Author: Yun, Hongruo
ISNI:       0000 0001 3576 2599
Awarding Body: University of Bristol
Current Institution: University of Bristol
Date of Award: 2008
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ADP-ribosylation factors (Arfs) are a family of Ras-related, low molecular mass (~20kDa), GTP-binding proteins that are expressed in all eukaryotes. They regulate intracellular vesicular trafficking along secretory and endocytic pathways and play a role in actin cytoskeleton reorganisation. The Arf family in mammals consists of six Arfs (Arfl-6), fifteen Arf-like (Aril-16), Sari and TR1M23 proteins. A few years ago, using a proteomic approach, a novel Arf protein, Arl8b, was discovered. However, Arl8b is not well studied yet. In this thesis, the biochemical and cellular characterisation of Arl8b has been discussed.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available