Use this URL to cite or link to this record in EThOS:
Title: Derivation, characterization of human embryonic stem cells and their GI to S transition mediated by NANOG
Author: Zhang, Xin
ISNI:       0000 0001 3577 3781
Awarding Body: University of Newcastle upon Tyne
Current Institution: University of Newcastle upon Tyne
Date of Award: 2008
Availability of Full Text:
Access from EThOS:
Human embryonic stem cells (ESC) can be maintained indefinitely in vitro and have the capacity for self-renewal and to remain in an undifferentiated state. Improvements in the derivation of human ESC lines are investigated in this study. To avoid the animal ingredient contamination during the immunosurgery procedure, entire blastocyst and mechanical removal of trophoectoderm cells were used and this proved to have similar derivation efficiency when compared to the plating of ICM isolated by immunosurgery.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available