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Title: Cell based strategies for cartilage repair
Author: Katopodi, Theoni
ISNI:       0000 0001 3595 489X
Awarding Body: University of Manchester
Current Institution: University of Manchester
Date of Award: 2008
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Chondrocytes are the only type of cell present in articular cartilage; they produce and maintain cartilage ECM, and lose their matrix production capacity when expanded in monolayer. Expanded chondrocytes at early passage, can partially regain their chondrogenic capacity with the help of biomaterials and growth factors. In this study the aims were to explore ways to improve the chondrogenic potential of expanded human OA chondrocytes in vitro. This would ultimately lead to the optimisation of chondrogenic differentiation protocols that could be employed in cartilage tissue engineering applications.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available