| Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491850 |
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| Title: | Structural and functional studies of P-glycoprotein using dual polarisation interferometry | ||||
| Author: | McDonnell, Catherine |
ISNI:
0000 0001 3623 8086
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| Awarding Body: | University of Manchester | ||||
| Current Institution: | University of Manchester | ||||
| Date of Award: | 2008 | ||||
| Availability of Full Text: |
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| Abstract: | |||||
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The membrane protein P-glycoprotein (Pgp) functions as an active exporter, coupling export of a wide range of drug molecules to ATP hydrolysis. In the absence of full length Pgp crystal structures demonstrating the structural changes which occur during the catalytic cycle, studies which provide insight on the details of structural changes are valuable.
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| Supervisor: | Not available | Sponsor: | Not available | ||
| Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||
| EThOS ID: | uk.bl.ethos.491850 | DOI: | Not available | ||
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