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Title: Structural and functional studies of P-glycoprotein using dual polarisation interferometry
Author: McDonnell, Catherine
ISNI:       0000 0001 3623 8086
Awarding Body: University of Manchester
Current Institution: University of Manchester
Date of Award: 2008
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The membrane protein P-glycoprotein (Pgp) functions as an active exporter, coupling export of a wide range of drug molecules to ATP hydrolysis. In the absence of full length Pgp crystal structures demonstrating the structural changes which occur during the catalytic cycle, studies which provide insight on the details of structural changes are valuable.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available