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Title: The impact of Toll-like receptors on antigen presentation by mouse macrophages
Author: Pupjain, Srijan
ISNI:       0000 0001 3502 9143
Awarding Body: University of Newcastle
Current Institution: University of Newcastle upon Tyne
Date of Award: 2008
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Toll-like receptors (TLRs) are a group of trans-membrane proteins playing important roles as pattern-recognition receptors (PRRs) of innate immunity that are mainly expressed on professional antigen presenting cells (APCs). Stimulation of APC with TLR ligands, a variety of Jnolecular components derived from microorganisms, triggers innate immunity and establishes adaptive immune responses. I studied the impact of TLR specific for bacterial components on antigen processing and presentation of protective antigen (PA) of B. anthracis by bone marrow macrophages from mice.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available