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Title: Development and utilisation of an In Vitro Assay for functional analysis of the Hepatitis C Virus p7 protein
Author: StGelais, Corine
ISNI:       0000 0001 3485 5902
Awarding Body: University of Leeds
Current Institution: University of Leeds
Date of Award: 2008
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The hepatitis C virus protein p7 is a 63 amino acid membrane protein that is able to oligomerise and functions as an ion channel in artificial bilayer systems, displaying sensitivity to amantadine as well as a range of other small molecule inhibitors. Consequently, p7 has been categorised as a member of the viroporin family; small virally encoded proteins that increase membrane permeability via their ability to oligomerise within host cell membranes.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available