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Title: Helicobacter pylori mediated hypergastrinaemia stimulates heparin-binding epidermal growth factor-like growth factor shedding via up-regulation of matrix metalloproteinase-7
Author: Yin, Yinfei
ISNI:       0000 0001 3575 2788
Awarding Body: University of Nottingham
Current Institution: University of Nottingham
Date of Award: 2008
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Gastric cancer is the second leading cause of cancer death worldwide. The strongest risk factor in the development of distal gastric cancer is Helicobacter Pylori (H. pylori) infection. Though the exact mechanism through which H. pylori contributes to gastric cancer progression is not yet fully elucidated, it may involve the downstream pathways triggered by hypergastrinaemia, which include induction of matrix metalloproteinases (mmps), and enhanced expression of growth factors.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available