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Title: Assessing cognitive and emotional effects of low dose typtophan depletion (TRD) in healthy participants
Author: Deepak, Kavita
ISNI:       0000 0001 3421 4128
Awarding Body: Oxford University
Current Institution: University of Oxford
Date of Award: 2008
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Objectives: Biological approaches to depression have been dominated by the serotonin theory, which suggests that clinical depression is associated with low serotonin function in the brain. However, the way in which serotonin might lead to mood change is still unclear. The relationship between serotonin dysfunction and psychological mechanisms identified by cognitive theories as being fundamental in the development of depression (e.g. core beliefs, cognitive distortions, negative automatic thoughts,) is particularly unclean The low dose tryptophan paradigm will be used to examine whether or how impaired serotonin function produces cognitive changes that map directly onto the clinical cognitive constructs that are targeted in CBT for depression.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (D.Clin.Psy.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available