Use this URL to cite or link to this record in EThOS:
Title: Characterisation of the Vertabrate inner-retinal photiopigments melanapsin (Opn4) and vertebrate ancient(VA) opsin
Author: Pires, Susana Salgado
ISNI:       0000 0001 3491 8491
Awarding Body: Oxford
Current Institution: University of Oxford
Date of Award: 2008
Availability of Full Text:
Full text unavailable from EThOS.
Please contact the current institution’s library for further details.
The most robust entrainment cue to the circadian clock is light. In response to this, organisms have evolved light detection mechanisms which allow them to measure and transduce irradiance information to specific centres in the brain. To perceive light, these receptors use photosensitive opsins that are remarkably divergent from those involved in image-forming photoreception. The main focus of this work was to understand if the photopigment function of the inner-retinal opsins can be inferred from their sequence and predicted structure. To this end we have isolated and characterised melanopsin and VA opsin from vertebrate species that have evolved under different environments.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available