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Title: Dynamics and oligomerization of urokinase plasminogen activator receptor (uPAR): a GIP-anchored receptor studied by fluorescence micro-spectoscopy.
Author: Malengo, Gabriele
ISNI:       0000 0001 3617 3980
Awarding Body: Open University
Current Institution: Open University
Date of Award: 2008
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This work is addressed to the search for functional links between GPI-protein monomeroligomer exchange and membrane dynamics and confinement. To this end, uPAR was chosen as a GPI-receptor involved in the regulation of cell adhesion, migration and proliferation. The work is focused on tracking the molecular dynamics and the homotypic interactions of uPAR, using fully fiinctional fluorescent protein-tagged chimeras expressed in HEK293 cells.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available