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Title: Studies on the Hsp90 chaperones of saccaromyces cerevisiae and humicola fuscoatra
Author: Nuttall, James Michael
ISNI:       0000 0001 3450 8257
Awarding Body: University of Sheffield
Current Institution: University of Sheffield
Date of Award: 2008
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Heat Shock Protein 90 (Hsp90) is a molecular chaperone, critically important for many of the proteins in eukaryotic cells (the Hsp90 "clients")- This project used the yeast Saccharomyces cerevisiae to investigate how Hsp90 regulates a model client protein (Slt2p/ERK5 MAPK) and how, by subtle Hsp90 mutation, this chaperone can become resistant to the Hsp90 inhibitor radicicol (RD).
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available