Use this URL to cite or link to this record in EThOS:
Title: Proliferation and patterning in the embryonic chick hypothalamic ventral midline
Author: Pearson, Caroline Alayne
ISNI:       0000 0001 3481 262X
Awarding Body: University of Sheffield
Current Institution: University of Sheffield
Date of Award: 2008
Availability of Full Text:
Access from EThOS:
Previous studies in the lab have shown that anterior-most floor plate cells undergo a change in fate in response to BMP-Tbx2 mediated signalling and give rise to ventral midline hypothalamic cells. In this study I have further characterised the ventral midline of the hypothalamus in the E4-E7 chick embryo. I demonstrate that the hypothalamic ventral midline is a complex structure comprised of distinct regions along its anterior-posterior axis. Fate-mapping studies demonstrate unequivocally that presumptive hypothalamic floor plate cells give rise to recognisable parts of the hypothalamus, In particular to the retrochiasmic, tubero-infundibular and mammillary regions and to distinct morphological structures, including the infundibulum and mammillary pouch.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available