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Title: Transient receptor potential signalling in normal human urothelial cell cultures.
Author: Agustus, Daniel Joseph
ISNI:       0000 0001 3399 6244
Awarding Body: York
Current Institution: University of York
Date of Award: 2008
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The urothelium is a highly compliant, transitional epithelium that enables the bladder to accommodate urine during filling by alteration of its surface area. The urothelium was traditionally thought of as a passive barrier to ions and solutes. More recent data suggested that the urothelium may have a sensory function arising from the urothelial stretch-triggered release of chemical mediators such as ATP, as demonstrated in rabbit and cat. intracellular caicium signalling known to induce vesicle fusion and ATP release from neuronal cells; a similar mechanism may be responsible for urothelial ATP release.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available