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Title: The evolution of an omni-directional bipedal robot
Author: Vaughan, Eric D.
ISNI:       0000 0001 3543 4173
Awarding Body: Sussex
Current Institution: University of Sussex
Date of Award: 2007
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The rescue of blocked replication forks is vital to the faithful duplication of a cell's entire genome once per cell cycle. Eukaryotic cells are equipped with the intra-S phase checkpoint that co-ordinates the multitude of cellular responses to replicative stress, and evidence implicate the checkpoint in reflating fork restart by recombination pathways. In this study, I investigate the role of various Schizosaccharomyces pombe checkpoint gene products in the regulation of recombination at forks arrested by a programmed protein barrier, Replication Termination Sequence 1 (RTS1).
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available