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Title: S1P,LPA and TRK a receptor expression, activation and signal transduction in various cell types
Author: Moughal, Noreen Akhtar
ISNI:       0000 0001 3427 8893
Awarding Body: Strathclyde
Current Institution: University of Strathclyde
Date of Award: 2008
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Lysophosphatidate (LPA) binds to a family of G-protein coupled receptors (GPCR). Three receptors belong to the endothelial differentiation gene (EDG) family, namely LPA1-3. whereas another two receptors LPA4-5 are evolutionary distant. The LPA1receptor couples to effectors via the heterotrimeric G-protein Gi to stimulate activation of the p42/p44 MAPK pathway.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available