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Title: Graph-Based Modelling and Reverse-Engineering of Biochemical Networks
Author: Mandel, Johannes Julius
ISNI:       0000 0001 3617 932X
Awarding Body: University of Ulster
Current Institution: Ulster University
Date of Award: 2007
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The term biological system encompasses all living systems within which components interact with one another on different levels of organisation. It is the goal of systems biology to explain how biological function emerges from the structure and dynamics of biological systems. The position of systems biology is that the functioning of biological systems is explicable in terms of the dynamic interaction of the components of that system. Reproducing these dynamics using computational models is therefore a promising way to inferring the causal relationships underlying biological function.This standpoint places systems thinking firmly on the centre stage of biological reasoning. However modelling complex systemic interactions is notoriously difficult for humans. It therefore becomes important to develop computer tools which support the modelling of biological systems. Such tools must harness the power of mathematics, engineering and computer science to support the creation of integrated and executable working models of biologigal systems.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available