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Title: The role of synaptic noise in cortical excitability
Author: Greenhill, Stuart David
ISNI:       0000 0001 3517 7648
Awarding Body: University of Bath
Current Institution: University of Bath
Date of Award: 2008
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The entorhinal cortex (EC) is a vital structure in the mammalian brain, implicated in the processes of learning and memory, and a possible site for the generation of seizures in temporal lobe epilepsy. Neurones in the EC are constantly bombarded with inhibitory and excitatory neurotransmitter. This background activity is thought to exert significant control on the excitability and function of neurones in cortical networks, with changes in the levels and proportion of background inhibition (IBg) and excitation (EBg) driving rhythmic oscillations in membrane potential, and even underlying the generation of epileptic seizures.
Supervisor: Jones, Roland Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: epilepsy ; electrophysiology ; entorhinal cortex