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Title: Urinary free thyroid hormones in children : an assay by gas liquid chromatography
Author: Mansour, Abdelhamid Abdelkadir
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1978
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Due to the trace levels of the free thyroid hormones in urine a variety of methods based on radiochemical techniques have been used for estimating free triiodothyronine aaid thyroxine, viz. competitive protein binding and radioimmunoassaye. While these techniques are currently employed, they suffer certain disadvantages, among which are the cross reaction of the urinary thyroid hormone metabolites with antibody in the radioimmunoassay system (Gaitan et al., 1975) and the competing of these metabolites for binding sites in the competitive-binding system (Finucane, 1976). Additionally, the above methods do not discriminate between bound and free urinary thyroid hormones (Burke & Shakespear, 1976). In this work the use of gas liquid chromatography as a method for the quantitation of urinary thyroid hormones is reported for the first time.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Biochemistry