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Title: Synthesis of certain tricyclic systems containing a bridgehead nitrogen
Author: Budhram, Ronald S.
ISNI:       0000 0001 3508 1910
Awarding Body: Loughborough University of Technology
Current Institution: Loughborough University
Date of Award: 1978
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We have shown that treatment of a quinoline Reissert compound carrying a blocking group at the 4-position with base in the presence of acrylonitrile can lead in modest yield to the pyrrolo[1,2-a]quinoline system and to an open chain ketone derived via an intermediate tetrahydropyrrolo[1,2-a]quinoline. This behaviour contrasts with the more ready formation of the pyrrolo[2,1-a]isoquinoline system by a similar process. Analogous condensation of the corresponding phthalazine Reissert compound with acrylonitrile in base has been shown to provide a straightforward route to the little known pyrrolo[2,1-a]phthalazine system.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available