Use this URL to cite or link to this record in EThOS: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.478477
Title: Mitochondrial genes and their expression in Saccharomyces cerevisiae
Author: Zanders, Edward Douglas
ISNI:       0000 0001 3576 7525
Awarding Body: University of Warwick
Current Institution: University of Warwick
Date of Award: 1976
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Abstract:
The more traditional interest in mitochondria as energy conserving organelles has in recent years been rivalled by studies related to membrane biogenesis. An extensive literature has shown that mitochondria are semi-autonomous with a system for the expression of their own genome in pleiotropy with nuclear genes and cytoplasmic protein synthesis. The presence of cytoplasmic genes in mitochondria provides a physical basis for the long observed phenomenon of maternal inheritance or "non-Mendelian" genetics, (1) in which the cytoplasmic phenotype is derived from the maternal parent only. This has been demonstrated in fungi, (2) amphibians, (3) and, more recently, in mammals (4, 5). The synthesis of mitochondrial membranes from pre-existing structures, as opposed to de novo synthesis, is in accordance with the partial genetic autonomy of these organelles. (6, 7). To this end, mitochondria possess DNA, RNA and a protein synthesis system.
Supervisor: Not available Sponsor: Science Research Council
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.478477  DOI: Not available
Keywords: QH Natural history ; QK Botany ; QP Physiology
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