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Title: Biosynthesis of gliotoxin and related compounds
Author: Patrick, Graham L.
ISNI:       0000 0001 3477 2381
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1979
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The open chain dipeptides, L-phenylalanyl-L-serine and L-seryl-L-phenylalanine were synthesised, radioactively labelled with 14C and 3H. Both precursors were poorly incorporated into gliotoxin, produced by Trichoderma viride. The isotope ratio measured in gliotoxin was different from those of the precursors which suggested that the precursors were cleaved by the fungus to their constituent amino-acids. It is believed that the amino-acids were then incorporated separately into gliotoxin.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available