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Title: An evaluation of mouse skin painting as a test for carcinogenesis : an investigation into cell kinetic and ultrastructural aspects of mouse skin painting, using polycyclic aromatic hydrocarbons, tobacco smoke condensate and non-carcinogenic irritant, with autoradiographic studies of hydrocarbon distribution
Author: Bibby, Michael Charles
ISNI:       0000 0001 2437 9332
Awarding Body: University of Bradford
Current Institution: University of Bradford
Date of Award: 1977
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Prior to the appearance of overt squamous cell carcinomata certain changes in the ultrastructure and the kinetic behaviour of the constituent epithelial cells have been described. They are found to occur following the application of known carcinogens to mouse skin. The changes have therefore been described as indicative of inevitable malignant transformation. The validity of this assumption has been challenged. If established it would be of immense value in screening for the presence of possible carcinogens in tobacco smoke, cosmetic preparations etc. They could replace with obvious economic value the present long term studies required.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available