| Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437382 |
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| Title: | Computational modelling and molecular dynamics simulations of ligand-gated ion channels | ||||||
| Author: | Amiri, Shiva |
ISNI:
0000 0001 3419 6636
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| Awarding Body: | University of Oxford | ||||||
| Current Institution: | University of Oxford | ||||||
| Date of Award: | 2006 | ||||||
| Availability of Full Text: |
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| Abstract: | |||||||
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Torpedo AChR structure was used to make models of other LGICs. Coarse-grain MD allowed the identification of residues in the TM domain interacting with the lipid-bilayer. Born energy profiles through LGIC pores reveal that the EC domain plays a key role in ion selectivity.
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| Supervisor: | Sansom, Mark S. | Sponsor: | Not available | ||||
| Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||||
| EThOS ID: | uk.bl.ethos.437382 | DOI: | Not available | ||||
| Keywords: | Ion channels ; Models ; Molecular aspects ; Molecular dynamics ; Ligands (Biochemistry) ; Synapses | ||||||
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