Objective: the overall aim of this thesis is to assess the 'feasibility' of using economic evaluation for the development of health care benefit packages in Thailand, specifically for selective use on a small number of 'difficult' coverage decisions within the high-cost element of the Universal Healthcare Coverage Scheme (UC). The term 'feasibility' consists of (i) the availability of economic evaluation information for decision-making, (ii) knowledge and understanding among the users, (iii) users' perception of the benefits of economic evaluation, and (iv) the relevance of economic evaluation to the interests of different stakeholders.