Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368448 |
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Title: | The biocompatibility of novel phosphorylcholine based biomaterials | ||||||
Author: | Barraud, Joanne Elizabeth |
ISNI:
0000 0001 3447 3947
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Awarding Body: | University of Brighton | ||||||
Current Institution: | University of Brighton | ||||||
Date of Award: | 2001 | ||||||
Availability of Full Text: |
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Abstract: | |||||||
Many conventional biomaterials fail to meet the demands required of them with respect to their surface and bulk properties. This problem can be addressed by developing novel biomaterials that have the desired bulk properties and increased biocompatibility. Alternatively the surfaces of biomaterials which have the desired bulk properties can be modified to increase their biocompatibility without compromising these bulk properties. Phosphorylcholine (PC) based coatings mimic the surface of biological membranes and so offer a novel method for modifying bulk materials, or can be incorporated into novel bulk biomaterials. One of the key issues of biocompatibility is the continual stimulation of the inflammatory response by biomaterials characterised in part by complement activation, macrophage adhesion and granulocyte activation.
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Supervisor: | Not available | Sponsor: | Not available | ||||
Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||||
EThOS ID: | uk.bl.ethos.368448 | DOI: | Not available | ||||
Keywords: | B000 Health Professions | ||||||
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