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Title: Plasticity related gene expression in the hippocampus
Author: Roberts, Lindsay A.
ISNI:       0000 0001 3524 3297
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1996
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Learning and the retention of the information as a memory produces changes in synaptic efficiency, the formation of new synapses and remodelling of existing synapses in the central nervous system. These plasticity-related changes are brought about by the modification of existing proteins and the synthesis of new proteins. One structure in the brain which is particularly associated with learning and memory is the hippocampus. Manipulation of synaptic transmission in this structure (in particular the phenomenon of long-term potentiation or LTP) is widely believed to be the mechanism which underlies mammalian synaptic plasticity This work was undertaken to further investigate the proteins which are affected by plasticity-related changes within the hippocampus, to improve understanding of why these changes occur and uncover more details about the mechanisms involved.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Synaptic transmission; Cognitive function