Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341625 |
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Title: | The origin of language-like features in DNA | ||||||
Author: | Hurworth, Allan Christopher |
ISNI:
0000 0001 3584 9811
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Awarding Body: | University of Southampton | ||||||
Current Institution: | University of Southampton | ||||||
Date of Award: | 2000 | ||||||
Availability of Full Text: |
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Abstract: | |||||||
Non-coding DNA is known to account for a significant proportion of the genomes of many organisms. The discovery by the use of three statistical tests - the Zipf analysis, the fluctuation analysis and the Shannon entropy - of linguistic features and long-range correlations within non-coding DNA has given rise to the suggestion that this higher-order structure may form the basis of a biological language in non-coding DNA. This work describes the development of a model to explain the origin of these language-like features in DNA. The model is based on observed genome reshaping processes - namely, transposable element insertion/excision events and point mutations - and involves the repeated duplication of transposable element target sites to build up repetitive blocks of DNA. This model shows that the observed language-like features can be generated by known genetic rearrangements and therefore suggests that any function of non-coding DNA has been acquired opportunistically, through the use of these language-like features.
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Supervisor: | Not available | Sponsor: | Not available | ||||
Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||||
EThOS ID: | uk.bl.ethos.341625 | DOI: | Not available | ||||
Keywords: | Non-coding; Linguistic features; Biological | ||||||
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