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Title: The effect of the substrate water activity on the growth of certain xerophilic fungi.
Author: Dallyn, Herbert.
ISNI:       0000 0001 3402 6434
Awarding Body: Polytechnic of the South Bank
Current Institution: London South Bank University
Date of Award: 1978
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Living processes have a universal requirement for water and microorganisms are not unusual in this respect. Lehninger (1975), in discussing the biological role of water, says that not only does water make up 70-90% of the weight of most forms of life, but it also represents the continuous phase of living organisms. This author details the various properties of water and its ionization products which are vital to the structure and the components of living cells and some of these are given below. Hydrogen bonding, although not peculiar to water, is likely to be of great importance in the biomolecular organization of the cell. Hydrogen bonds can form and break much faster than most co-valent bonds in aqueous systems: a fact which coupled with their geometric specificity and orientation has given hydrogen bonds a great biological advantage over co-valent bonds in biomolecular phenomena that must occur at a high rate in processes such as the unfolding of proteins into their native conformations. The hydrophobic interactions which occur in cellular components are fundamental to membrane structure. Harrison and Lunt (1975) state that whilst the composition of membranes varies with their source they generally contain approximately 40% of their dry weight as lipid and 60'%-as protein, held together in a complex by non-bonded interactions. Ca-bonded to either the lipid or to the protein moiety is carbohydrate forming 1-10; % of the total dry weight. Additional to the above components, membranes contain some 20% of their total weight as water which is tightly bound, and essential to the maintenance of the membrane structure.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available