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Title: Synthetic and antimicrobial studies of nitroimidazole analogues
Author: Adebayo, Adelaide Titilayo Oluronke Morenike
ISNI:       0000 0001 3398 2213
Awarding Body: Loughborough University of Technology
Current Institution: Loughborough University
Date of Award: 1988
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New 2-, 4- and 5-nitroimidazole analogues were synthesised using the following methods: (i) SRN1 free radical reaction between nitroimidazole anion and halonitro substrates; (ii) oxidative addition of the anion of 2-nitropropane to nitroimidazole anions. N-1-alkyl derivatives of imidazole, benzimidazole, 5-nitrobenzimidazole, 5- and 6-nitroindazole were similarly prepared. These compounds showed antimicrobial activity; anaerobes were more sensitive than aerobes.
Supervisor: Not available Sponsor: Lorenzayo Ltd (Lagos, Nigeria)
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Synthesis of nitroimidazole