A quaternion-Hermitian manifold, of dimension at least 12, with closed fundamental 4-form is shown to be quaternionic Kähler. A similar result is proved for 8-manifolds. HyperKähler metrics are constructed on the fundamental quaternionic line bundle (with the zero-section removed) of a quaternionic Kähler manifold (indefinite if the scalar curvature is negative). This construction is compatible with the quaternionic Kähler and hyperKähier quotient constructions and allows quaternionic Kähler geometry to be subsumed into the theory of hyperKähler manifolds. It is shown that the hyperKähler metrics that arise admit a certain type of SU(2)- action, possess functions which are Kähler potentials for each of the complex structures simultaneously and determine quaternionic Kähler structures via a variant of the moment map construction. Quaternionic Kähler metrics are also constructed on the fundamental quaternionic line bundle and a twistor space analogy leads to a construction of hyperKähler metrics with circle actions on complex line bundles over Kähler-Einstein (complex) contact manifolds. Nilpotent orbits in a complex semi-simple Lie algebra, with the hyperKähler metrics defined by Kronheimer, are shown to give rise to quaternionic Kähler metrics and various examples of these metrics are identified. It is shown that any quaternionic Kähler manifold with positive scalar curvature and sufficiently large isometry group may be embedded in one of these manifolds. The twistor space structure of the projectivised nilpotent orbits is studied.