Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245667 |
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Title: | Radical cyclisations onto imidazoles | ||||||
Author: | Aldabbagh, Fawaz |
ISNI:
0000 0001 3410 2839
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Awarding Body: | Loughborough University | ||||||
Current Institution: | Loughborough University | ||||||
Date of Award: | 1997 | ||||||
Availability of Full Text: |
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Abstract: | |||||||
This thesis describes the development of new pathways towards the synthesis of novel antimicrobial (and anticancer) agents. Two synthetic protocols based on free radical chemistry are studied, which are used to access polycyclic heterocyclic compounds of potential biological importance. Both these procedures involve the generation of radicals using Bu3SnH and AIBN initiators, and the subsequent intramolecular radical cyclisation onto the imidazole ring. Radical cyclisations onto benzimidazoles and pyrroles are also described.
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Supervisor: | Not available | Sponsor: | Loughborough University | ||||
Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||||
EThOS ID: | uk.bl.ethos.245667 | DOI: | Not available | ||||
Keywords: | Pyrrole; Antimicrobial agents; Anticancer | ||||||
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