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Title: Cardiovascular disease and medication use associated with exposure to aircraft noise, road traffic noise and air pollution in populations living near airports
Author: Floud, Sarah Katherine
Awarding Body: Imperial College London
Current Institution: Imperial College London
Date of Award: 2012
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Noise is a significant environmental problem; epidemiological evidence that noise from road traffic and aircraft may be damaging to health has been increasing. This thesis uses data from the HYENA (HYpertension and Exposure to Noise near Airports) multi-centre study. Earlier HYENA studies suggested that noise exposure increased the risk of hypertension and other risk factors for cardiovascular disease, through blood pressure spikes, reduced night-time dipping of blood pressure and raised morning salivary cortisol. This thesis found that long-term exposure to aircraft noise was associated with increased prevalence of cardiovascular disease and with the use of anti-hypertensive and anxiolytic medication. Road traffic noise was also associated with cardiovascular disease and additionally with antacid use in men. These are new findings with significant implications for public policy. Airports generate road traffic, with associated air pollution increasing the risk of cardiovascular disease. An analysis was therefore undertaken into whether the association between cardiovascular disease and road traffic noise was confounded by air pollution or if there was interaction between the exposures. Mutual confounding by noise and air pollution was found in separate analyses of three countries within HYENA. It is possible that aspects of the home environment, insulation, open windows and room orientation, affect exposure to noise and thus modify health risks. Associations between cardiovascular disease and road traffic noise were found for participants whose rooms faced the road and for those who had sound proofing installed in their home, suggesting the latter is a marker for higher exposure and/or sensitivity to noise. The effect of opening windows on the association between cardiovascular disease and noise was less clear, with an association with aircraft noise but not with road traffic noise.
Supervisor: Hansell, Anna ; Clarke, Charlotte ; Blangiardo, Marta Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available