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Title: Modulation of hippocampal gamma oscillations by acetycholine
Author: Betterton, Ruth Traer
ISNI:       0000 0004 5917 3432
Awarding Body: University of Bristol
Current Institution: University of Bristol
Date of Award: 2015
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Neuronal oscillations involve the rhythmic, synchronous firing of populations of cells across a range of frequencies. Gamma oscillations (30 - 100Hz) occur during attention, sensory processing and learning and memory. Acetylcholine (ACh) release in the hippocampus is associated with increases in gamma oscillatory power and disruption of cholinergic inputs to the hippocampus and selective knockout of ACh receptor subtypes (AChRs) alter oscillatory activity. This suggests that ACh has a role in the modulation of gamma oscillations. To investigate this process we have utilised both in vitro brain slice and mathematical models.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available