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Title: Constructing phylogenetic networks based on trinets
Author: Oldman, James
ISNI:       0000 0004 5915 8099
Awarding Body: University of East Anglia
Current Institution: University of East Anglia
Date of Award: 2015
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The motivation of phylogenetic analysis is to discover the evolutionary relationships between species, with the broader aim of understanding the origins of life. Our understanding of the molecular character- istics of species through DNA sequencing permanently changed the approach to understanding the evolution of species. Indeed, the ad- vancement of technology has played a major role in the fast sequencing of DNA as well as the use of computers in solving biological problems in general. These evolutionary relationships are often visualised and represented using a phylogenetic tree. As a natural generalisation of phylogenetic trees, phylogenetic networks are used in biology to rep- resent evolutionary histories that contain reticulate, or non-treelike events such as recombination, hybridisation and horizontal gene trans- fer. The reconstruction of explicit phylogenetic networks from biolog- ical data is currently an active area of phylogenetics research. Here we consider the problem of constructing such networks from trinets, that is, phylogenetic networks on three leaves. More speci�cally, we present the SeqTrinet and TriLoNet methods, which form a supernet- work based approach to constructing level-1 phylogenetic networks directly from multiple sequence alignments.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available