Use this URL to cite or link to this record in EThOS:
Title: Rapid assessment of corticospinal excitability using transcranial magnetic stimulation
Author: van de Ruit, Mark Laurens
ISNI:       0000 0004 5917 4996
Awarding Body: University of Birmingham
Current Institution: University of Birmingham
Date of Award: 2016
Availability of Full Text:
Access from EThOS:
Access from Institution:
Human motor system plasticity can be quantified using single pulse transcranial magnetic stimulation (TMS) to measure corticospinal excitability. TMS can be used to produce excitability maps and to examine the stimulus-response (SR) relationship. The overall aims of this thesis are (1) to demonstrate that TMS mapping and SR curves can be acquired much faster than has been traditionally possible and (2) that these techniques can be used to study internally externally driven plasticity. By modifying the TMS delivery, it is demonstrated that both the TMS map and the SR curve can be reliably produced in approximately two minutes. These techniques were then used to examine internally driven plasticity via mirror training and visuomotor tracking learning and externally driven plasticity via transcranial alternating current stimulation. Changes in corticospinal excitability were found to be variable both for internally as externally driven plasticity. Nonetheless, these studies highlight that it is possible to rapidly assess changes in corticospinal excitability.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: QP Physiology