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Title: In vitro studies on the effect of remineralising treatments on hypomineralised enamel and subsequent orthodontic bonding
Author: Abdullah , Ahmed
Awarding Body: University of Bristol
Current Institution: University of Bristol
Date of Award: 2014
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Molar incisor hypomineralisation (Mill) is a general and chronological hypomineralisation of systemic origin of the pelmanent first molars and incisors and appears as demarcated opacities ranging from white to dark brown spots (Weerheijm et al., 2001a). To date there is little published research on MIH and 011hodontics, the use of remineralising agents and subsequent orthodontic bonding. This DDS research project on MIH comprised three parts, namely: An investigation into sterilisation of MIH specimens Tooth specimens for use in laboratOlY studies must be disinfected to protect laboratory personnel and equipment from infectious agents. There are many different disinfection! sterilisation regimens available and the effect they may have on MIH affected enamel is unknown. The objective of this part of the study was to investigate the effect of three sterilisation methods (gamma ilTadiation, cold plasma and ethylene oxide) on the mechanical properties and erosion susceptibility of hypomineralised human enamel in vitro, and to compare this to the usual method of Thymol immersion. The results showed that ethylene oxide, gamma ilTadiation and thymol did not affect the surface harness of hypomineralised enamel post sterilisation, whereas cold plasma had a significant softening effect. The effect of remineralising treatments on MIH affected enamel The object of this part of the laboratOlY study was to investigate the effect of six different remineralising treatments on the demineralisation of hypomineralised enamel when subjected to citric acid immersion. Enamel specimens (7-groups) from human first molars exhibiting MIH were initially immersed in a sluny of 1450ppm NaF (groups: GI-G3), or 5000ppm NaF (groups: G4-G6). The seventh group (G7) (no treatment) acted as the control. The specimens from each group (5 specimens in each group) were subjected to five cycles of immersion in 0.3% citric acid solution (10 secs), followed by rinsing and then immersion in artificial saliva (60mins). Following this the groups were treated with slurries of the following: 1450ppm NaP toothpaste (Gl), 1450ppm NaF toothpaste with casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) gel (G2), 1450ppm NaF toothpaste with CPP-ACPF gel and 22500ppm NaF varnish (G3); 5000ppm NaF toothpaste (G4), 5000ppm NaF toothpaste with CPP-ACPF gel (G5), 5000ppm NaF toothpaste with CPP-ACPF gel and 22500ppm NaF varnish (G6).
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (D.D.S.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available