Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676511
Title: Mechanisms underlying the interaction between PPARα and NADPH oxidases in the hypertrophic cardiomyocyte
Author: Harvey
Awarding Body: Queen's University Belfast
Current Institution: Queen's University Belfast
Date of Award: 2014
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Abstract:
Nox2 nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and peroxisome proliferator-activated receptor-alpha (PPARa) play important roles in the development of chronic heart failure (CHF) with evidence suggesting that an interaction between PPARa and Nox2 may occur during CHF. The aim of this study was to investigate the roles that PPARa and Nox2 play during cardiac hypertrophy and identify whether an interaction between the two occurs following transverse aortic constriction (TAC) and identify potential candidates that mediate an interaction.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.676511  DOI: Not available
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