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Title: Functional hydrogel coatings for Biomedical applications
Author: Corbett, Daniel James
ISNI:       0000 0004 5372 5742
Awarding Body: Queen's University Belfast
Current Institution: Queen's University Belfast
Date of Award: 2014
Availability of Full Text:
Full text unavailable from EThOS. Thesis embargoed until 01 Dec 2019
Biomedical devices are commonly used in all areas of healthcare, These devices, which range from contact lenses through to endotracheal tubes, are most often fashioned from materials which allow the device to carry out its function thoroughly, but in doing so render the device susceptible to a number of complications. Two of the most major complications are that of device infection and poor frictional behaviour at the interface of the device and human tissue. This thesis details the development and characterisation of various polymeric systems which allow the resolution of these problems. With regard to infection, well established photodynamic techniques are further developed to provide a system which can bring about effective prevention of infection for prolonged durations of time, leading to a wide range of advantages, potentiating the function of the device. Biomaterial frictional behaviour is improved in a number of ways, including the development of next generation device coatings which are more easily wetted, offer improved biocompatibility, and also offer an improved tenacity of effect. Moreover, further work in this thesis has led to the development of successful photochemical attachment pathways for the addition of such coatings to the surface of commonly used biomaterial substrates.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available