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Title: Gene expression and cleavage arrest in the human embryo
Author: Artley, J. K.
Awarding Body: University of Leicester
Current Institution: University of Leicester
Date of Award: 1993
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In vitro fertilisation and embryo transfer (IVF-ET) is now an accepted part of clinical practice for the treatment of infertility offering live birth rates in the region of 24% per cycle when three embryos are returned to the uterus However analysis of success in terms of the number of established conceptions per embryo returned reveals that only 10.9% of embryos transferred implant. Achieving improved success for IVP-ET, especially following the replacement of a single embryo in order to reduce the risk of multiple pregnancy is undoubtedly dependent on an improved understanding of the mechanisms that lead to embryonic failure.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available