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Title: Health related quality of life and coping behaviours in men receiving radiotherapy and neo-adjuvant hormone treatment for prostate cancer: a quantitative longitudinal study
Author: McSorley , Oonagh
ISNI:       0000 0004 5369 3576
Awarding Body: Ulster University
Current Institution: Ulster University
Date of Award: 2014
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Men with localised prostate cancer can now expect to live longer with the disease and the side-effects of treatment than a decade ago. These side effects include urinary, bowel and sexual dysfunction which can affect their quality of life. Aim: There is a lack of information on how radiotherapy with neo-adjuvant hormone treatment affects men's quality of life over one year post-radiotherapy and how they cope with the disease and side-effects during this time. This study aims to address these gaps. Method: One hundred and forty-nine men who were about to undergo radiotherapy and neo-adjuvant hormone treatment for localised prostate cancer participated in this longitudinal study. They completed the EORTC QLQ C-30 & PR25 and the Brief Cope scale at four times (prior to radiotherapy, at four to six weeks post-radiotherapy; at six months and one year post-radiotherapy). The response rate was over 90% at each time-point. Results: Men reported the biggest decline in all aspects of health related quality of life at 4-6 weeks after radiotherapy, generally followed by improvements in health between six months and a year after treatment. Those who were experiencing late urinary side-effects, one year after radiotherapy had poor urinary function prior to radiotherapy. Some men who reported acute bowel effects at 4-6 weeks after radiotherapy developed late effects. Coping and HRQoL in men receiving prostate cancer treatment were influenced by the individual's life circumstances inclusive of age, spousal support and their perceived HRQoL as well as time (pre and post treatment). Conclusion: Psycho-social interventions in follow-up care need to be developed and these need to be flexible enough to take account of the individual physical and psycho-social needs of men with prostate cancer pre and post-radiotherapy. They are particularly vulnerable in the immediate post-radiotherapy period. Men with little social support may also be most in need of help.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available