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Title: Imaging physiological ABC transporter expression and its relation to disease using Tc-99m-hexakis-methoxy-isobutyl isonitrile (Tc-99m-MIBI)
Author: Dizdarevic, Sabina
ISNI:       0000 0004 5363 4453
Awarding Body: University of Brighton
Current Institution: University of Brighton
Date of Award: 2015
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Tc-99m-MIBI is a substrate for ATP-binding cassette (ABC) transporter proteins, including P-glycoprotein (P-gp), and has been used to image their expression, mainly in cancer. Imaging P-gp expression may have a role in renal transplantation and investigating drug toxicity. The aim of the project was to develop a functional imaging assay for ABC-transporters using Tc-99m-MIBI.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: A000 Medicine