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Title: Clinical studies of erectile impotence in diabetic men
Author: McCulloch, David K.
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1984
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The aims of this thesis were to establish the prevalence of erectile impotence in male diabetics, investigate the aetiology and follow the natural history in order to gain a fuller understanding of the condition. From a cohort of 541 diabetic men aged 20-59 years it was found that 190 (35%) were impotent. Impotence was associated with age, retinopathy and symptomatic peripheral and autonomic neuropathy. Subgroups of patients were investigated in more detail using cardiovascular autonomic function tests and by the non-invasive evaluation of bladder function. Impotent diabetic men had more abnormalities in bladder function. The severity of bladder dysfunction correlated with the degree of abnormality in cardiovascular autonomic function tests. Four hundred and sixty-six of the original cohort were followed prospectively over a five year period. Only 11 of those originally impotent had regained potency while 78 out of 275 who were originally potent became impotent. Apart from age, the most important factors, present originally which increased the likelihood of developing impotence were poor diabetic control, heavy alcohol intake and the presence of retinopathy or intermittent claudication. Sixty-three patients died, but impotence per se was not associated with increased mortality. The thesis concludes by discussing the implications of these data for the prevention and management of erectile impotence in diabetic men.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available