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Title: The effect of theileriosis on the reproductive function of Boran/Friesian cross heifers
Author: Rumberia, Rufus Mburea
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1992
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This thesis describes studies that were undertaken to evaluate the effect of T.parva infection on the reproductive function of Boran/Friesian cross heifers. The study was conducted in four separate experiments. In Experiments 1 and 2, the animals were monitored for cyclical status post-infection. In Experiments 3 and 4, the infected animals were divided into two groups: one group was monitored for cyclical status and the other for both cyclical and pregnancy status after exposure to a bull. The reproductive function was assessed by routine monitoring of oestrous behaviour, palpation of the genital reproductive tract per rectum and determination of serum progesterone (P4) concentrations. Further, in view of observed acyclicity in the early work, attempts were made to assess the pituitary response to gonadotrophin releasing hormone (GnRH) in a group of animals (Ch.5) in an attempt to explain partly the mechanisms involved in the impairment. Animals were monitored for the progression of disease by clinical and parasitological responses. Further, subject to death or sacrifice, a macroscopic and histological examination of target and various other organs and tissues was undertaken in an effort to establish the part played by observable pathological changes in the development of impaired reproductive function. In Experiment 1, ten heifers were infected with 1:20 T.parva stabilate while four others remained as uninfected controls. Two of the infected animals died on days 17 and 29. Clinical reactions in the reovered animals ranged from mild to moderate. P4 profiles and ovarian structures revealed that three of eight recovered animals had luteal dysfunction post-infection although two of the three showed clinical oestrus during this particular period. The other five recovered animals cycled regularly. The results from clinical and pathological studies did not indicate any direct adverse effect of infection on reproductive function. All the four controls cycled throughout the study period.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available