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Title: Genetic and physical mapping of autosomal dominant polycystic kidney disease
Author: Pound, Susan Elizabeth
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1994
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A sample of 35 families with ADPKD from central Scotland, previously typed with two markers from the PKD1 region [3'HVR. However, there is one recombinant with CMM65 (D16S84), and one with 26-6 (D16S125), which localises PKD1 to between these markers. In order to obtain cloned DNA from this genetically defined region of interest, spanning approximately 750 kb of DNA, yeast artificial chromosomes (YACs) were isolated from available libraries.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available