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Title: The genetics of schizophrenia and affective psychoses
Author: Muir, Walter J.
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 2009
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This thesis reviews published research conducted over almost 25 years by myself as part of the psychiatric genetics group in the Division of Psychiatry, University of Edinburgh. Our studies of the genetic bases for schizophrenia and affective psychoses have created and analysed large and detailed clinical resources. Novel methods have been used to study these from biomarker definitions of the phenotype through to the molecular cytogenetic approach to cloning disrupted susceptibility genes from chromosomal breakpoints. As well as altering our concepts of the boundaries between schizophrenia and affective disorders these studies have revealed a series of key candidate genes including DISC1, NPAS3 and GRIK4.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (D.Sc.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available